Transactive Response DNA-binding Protein 43 (TDP-43) Regulates Alternative Splicing Of Tau Exon 10:
Hyperphosphorylation and aggregation of the neuronal protein tau are responsible for neurodegenerative diseases called tauopathies. Dysregulation of the alternative splicing of tau exon 10 results in Read More »
Author: Jianlan Gu, Feng Chen, Khalid Iqbal, Cheng-Xin Gong, Xinglong Wang, Fei Liu
Contributor: eb™ Research Team
From Animal Models To Human Disease: A Genetic Approach For Personalized Medicine In ALS
Amyotrophic Lateral Sclerosis (ALS) is the most frequent motor neuron disease in adults. Classical ALS is characterized by the death of upper and lower motor neurons leading to progressive paralysis. Read More »
Author: Vincent Picher-Martel, Paul N. Valdmanis, Peter V. Gould, Jean-Pierre Julien, Nicolas Dupré
Contributor: eb™ Research Team
Genetic Mutations In RNA-binding Proteins And Their Roles In ALS
Mutations in genes that encode RNA-binding proteins (RBPs) have emerged as critical determinants of neurological diseases, especially motor neuron disorders such as amyotrophic lateral sclerosis Read More »
Author: Katannya Kapeli, Fernando J. Martinez, Gene W. Yeo
Contributor: eb™ Research Team
Rab-dependent Cellular Trafficking And Amyotrophic Lateral Sclerosis
Rab GTPases are becoming increasingly implicated in neurodegenerative disorders, although their role in amyotrophic lateral sclerosis (ALS) has been somewhat overlooked. However, dysfunction of Read More »
Author: S. Parakh, E. R. Perri, C. J. Jagaraj, A. M. G. Ragagnin, J. D. Atkin
Contributor: eb™ Research Team
LEADERSHIP TRAITS AND THEIR IMPACT ON MARKET STRATEGIES
Sri Lanka holds a dominant position as a leading exporter of black tea. It has a reasonably diversified product line including both orthodox and CTC teas. Sri Lankan tea industry is operating in a Read More »
