Background: People with Disables have great contributions in countries’ development that they endowed with great accumulation of knowledge and skill through participations in different production sector like agriculture even stigmatized. Based on this inception, this research activity was initiated with objectives of scale up the best climate smart agriculture practices to people with disable, engage people with disable in technology promotion and scaling up the lessons, and disseminate the knowledge and skill to people with disable in alternative income generation enterprises. Materials and Methods: To achieve these all objectives, Babile district Erer Ibada and Ifadin kebeles were selected where people with disable these infected by leprosy disease. Accordingly, 27 PwD were involved in study and provided training on different topic of agricultural technologies both on pre- and post-harvest production, and provided with many inputs for pre-and post-harvests. After all, two sorghum varieties Melkam and Dekeba; Two Haricot-bean varieties KTAB1 and Batu with full packages were sown on provided land. Results: As a result, Malkam variety performed high yielder 38.5 quintal/hectare compare to Dekeba yielded 31.5 quintal/hectare, similarly Melkam variety marketed more 1005 quintal because of its demand on market in turn they earned good income. Moreover, the Haricot-bean variety KTAB1 yielded high 14.5 quintal/hectare compare to Batu yielded 12.8 quintal/hectare, however, Batu variety is marketed as produced because of its high demand in both urban and rural areas. Conclusion and policy implications: For all these technology implementations, different networking and media coverage by mass media like regional and national TV programs, FM Radios, field days, workshops and published and printing materials were used. Therefore, it is recommended that scaling up of these research activities lessons and experiences by governments, no-governments organizations and other stakeholders should mainstream People with Disable in their development and research programs.