The Hofstede Cultural Dimensions is a model developed by Geert Hofstede, a Dutch psychologist working in human resources at IBM in the 1970s. It is used to measure cultural differences between different countries and explain how these differences influence society and the behavior of individuals within that society. Also known as the theory of cultural dimensions, this theory explains how differences in culture affect the behavior of individuals and societies. This article compares the cultural differences between the United States and Turkey and their impact on human resource management within the context of the Hofstede Cultural Dimensions. The Hofstede Cultural Dimensions is a model used to measure cultural values and behaviors and consists of the following dimensions: power distance, individualism versus collectivism, masculinity versus femininity, uncertainty avoidance, short-term versus long-term orientation, and indulgence versus restraint. This research utilizes the method of secondary data analysis, which involves using existing data, to analyze the cultural differences between the United States and Turkey within the context of the Hofstede Cultural Dimensions. The article aims to demonstrate how these cultural differences impact human resource management. Human resource professionals can benefit from this comparison by understanding these differences and developing strategies that take the cultural context into account. By analyzing the cultural differences between the United States and Turkey through the lens of the Hofstede Cultural Dimensions, this article highlights the effects of these differences on human resource management.