This article reflects on the future of artisanry in the context of the Metaverse in Brazil, considering artisanry relationship with fashion. Hence, the Metaverse is described through NFTs, blockchain, as well as avatars and cyborgs. Then, artisanry, especially in Brazil, and its relationship with fashion in contemporaneity are described. This study aimed to answer the following research question: considering the profile of Brazilian artisans, how would their artisanal production adapt to the Metaverse? To achieve the results, we used bibliographic, descriptive, and qualitative research to analyze the literature and to develop discussions based on distinctive ways of building objects in virtual universes. We concluded that artisans will have to develop interdisciplinary skills linked to computerized technology to remain competitive in the market, added to investments and stimuli from public and private institutions.