Genome and Bio-Tech

Article

QUANTUM CASCADE LASER SYSTEMS BASED ON NANOMATERIALS FOR BIOLOGICAL APPLICATIONS: SIMULATION AND

Our research subject aims to study a laser system based on nanomaterials, for possible biological applications. So far we have examined the performance of a quantum well structure, composed of a Read More »

Date: 07/01/2024
Author: EL GHAZI Haddou, ALHIMA Meryem
Contributor: eb™ Research Team
Article

Molecular Pathology And Genetic Advances In Amyotrophic Lateral Sclerosis: An Emerging Molecular

Research into amyotrophic lateral sclerosis (ALS) has been stimulated by a series of genetic and molecular pathology discoveries. The hallmark neuronal cytoplasmic inclusions of sporadic ALS (sALS) Read More »

Date: 11/22/2011
Author: Paul G. Ince, Pamela J. Shaw, Michael J. Strong, Hitoshi Takahashi, Stephen B. Wharton, Janine Kirby, J. Robin Highley
Contributor: eb™ Research Team
Article

TDP-43 Proteinopathy And ALS: Insights Into Disease Mechanisms And Therapeutic Targets

Therapeutic options for patients with amyotrophic lateral sclerosis (ALS) are currently limited. However, recent studies show that almost all cases of ALS, as well as tau-negative frontotemporal Read More »

Date: 02/05/2015
Author: Emma L. Scotter , Han-Jou Chen , Christopher E. Shaw
Contributor: eb™ Research Team
Article

Transactive Response DNA-binding Protein 43 (TDP-43) Regulates Alternative Splicing Of Tau Exon 10:

Hyperphosphorylation and aggregation of the neuronal protein tau are responsible for neurodegenerative diseases called tauopathies. Dysregulation of the alternative splicing of tau exon 10 results in Read More »

Date: 05/09/2017
Author: Jianlan Gu, Feng Chen, Khalid Iqbal, Cheng-Xin Gong, Xinglong Wang, Fei Liu
Contributor: eb™ Research Team
Article

From Animal Models To Human Disease: A Genetic Approach For Personalized Medicine In ALS

Amyotrophic Lateral Sclerosis (ALS) is the most frequent motor neuron disease in adults. Classical ALS is characterized by the death of upper and lower motor neurons leading to progressive paralysis. Read More »

Date: 07/11/2016
Author: Vincent Picher-Martel, Paul N. Valdmanis, Peter V. Gould, Jean-Pierre Julien, Nicolas Dupré
Contributor: eb™ Research Team
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